More than 390 articles have been published by the members of Gruppo Otologico till date. The scientific articles published by the members of the Gruppo Otologico have always featured in the most prestigious journals with the highest impact factor. This includes invited articles & reviews, original series, research papers, case reports and commentaries. Here is the list of the articles published.

Incomplete and false tract insertions in cochlear implantation: retrospective review of surgical and auditory outcomes

European Archives of Oto-Rhino-Laryngology
Ashish Vashishth, Andrea Fulcheri, Maurizio Guida, Antonio Caruso, Mario Sanna

Abstract

OBJECTIVE:
To evaluate incidence, demographics, surgical, and radiological correlates of incomplete and false tract electrode array insertions during cochlear implantation (CI). To evaluate outcomes in patients with incomplete electrode insertion (IEI).

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Paragangliomas arise through an autonomous vasculo-angio-neurogenic program inhibited by imatinib

Paragangliomas arise through an autonomous vasculo-angio-neurogenic program inhibited by imatinib

Acta Neuropathol DOI 10.1007/s00401-017-1799-2
Mario Sanna et al.

Tumours can be viewed as aberrant tissues or organs sustained by tumorigenic stem-like cells that engage into dysregulated histo/organogenetic processes.

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Temporal Bone Meningo-Encephalic-Herniation: Etiological Categorization and Surgical Strategy

Temporal Bone Meningo-Encephalic-Herniation: Etiological Categorization and Surgical Strategy

Otol Neurotol 38
Golda Grinblat, Manjunath Dandinarasaiah, Sampath Chandra Prasad, Gianluca Piras, Enrico Piccirillo, Andrea Fulcheri, and Mario Sanna

Abstract

OBJECTIVE:
To study the clinical presentation, intraoperative findings and surgical management in meningo-encephalic-herniation (MEH) based on the etiology.

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Decision Making in the Wait-and-Scan Approach for Vestibular Schwannomas: Is There a Price to Pay in Terms of Hearing, Facial Nerve, and Overall Outcomes?

Decision Making in the Wait-and-Scan Approach for Vestibular Schwannomas: Is There a Price to Pay in Terms of Hearing, Facial Nerve, and Overall Outcomes?

Neurosurgery 0:1–13, 2017
Sampath Chandra Prasad, MS, DNB, FEB-ORLHNS; Uma Patnaik, MS, DNB; Golda Grinblat, MD; Annalisa Giannuzzi, MD; Abdelkader Taibah, MD; Mario Sanna, MD

Abstract

BACKGROUND:
The wait-and-scan modality has emerged as an important strategy in the management of vestibular schwannoma (VS) as it has been demonstrated that many tumors grow slowly or do not show any growth over long periods.

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Cochlear Implantation in Cochlear Ossification: Retrospective Review of Etiologies, Surgical Considerations, and Auditory Outcomes

Otol Neurotol. 2017 Oct 23
Ashish Vashishth, Andrea Fulcheri, Sampath Chandra Prasad, Margherita Bassi, Gianluca Rossi, Antonio Caruso, and Mario Sanna

Abstract

OBJECTIVE:
1) To review the surgical and auditory outcomes and complications of cochlear implantation in cases with cochlear ossification.
2) To evaluate association between the extent and etiology of ossification to outcomes.

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Petrous Apex Cholesterol Granulomas: Outcomes, Complications, and Hearing Results From Surgical and Wait-and-Scan Management

Otol Neurotol. 2017 Oct 4
Golda Grinblat, Ashish Vashishth, Franco Galetti, Antonio Caruso, Mario Sanna

Abstract

OBJECTIVE:
1. To analyze the surgical outcomes in the management of petrous apex cholesterol granulomas (PACG) with a brief literature review.
2. To evaluate the importance of wait-and-scan management option.

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Surgical Management of Intrinsic Tumors of the Facial Nerve

Neurosurgery, nyx489
Sampath Chandra Prasad, MS, DNB, FEB-ORLHNS; Melissa Laus, MD; Manjunath Dandinarasaiah, MS; Enrico Piccirillo, MD; Alessandra Russo, MD; Abdelkader Taibah, MD; Mario Sanna, MD

Abstract

BACKGROUND:
Intrinsic tumors of the facial nerve are a rare entity. Dealing with this subset of tumors is challenging both in terms of decision making and surgical intervention.

OBJECTIVE:
To review the outcomes of surgical management of facial nerve tumors and cable nerve graft interpositioning.

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Cochlear Implantation in Otosclerosis: Surgical and Auditory Outcomes With a Brief on Facial Nerve Stimulation

Otology and Neurotology 38:e345–e353, 2017.
Ashish Vashishth, Andrea Fulcheri, Gianluca Rossi, Sampath Chandra Prasad, Antonio Caruso, and Mario Sanna

Abstract

OBJECTIVE
1) To review the surgical and auditory outcomes in patients of cochlear implantation in otosclerosis. 2) To review complications and postimplantation facial nerve stimulation (FNS). 3) To compare the auditory outcomes between patients displaying cochlear ossification to the nonossified ones.

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Subtotal petrosectomy: surgical technique, indications, outcomes and comprehensive review of literature

4. Laryngoscope, 2017.
Sampath Chandra Prasad, MS, DNB, FEB-ORLHNS; Valeria Roustan, MD; Gianluca Piras, MD; Antonio Caruso, MD; Lorenzo Lauda, MD; Mario Sanna, MD

Abstract

OBJECTIVES/HYPOTHESIS
To describe the technique of subtotal petrosectomy (STP), to analyze the outcomes, and to review the literature.

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Surgical technique and results of cable graft interpositioning of the facial nerve in lateral skull base surgeries: experience with 213 consecutive cases

2017, Journal of Neurosurgery
Sampath Chandra Prasad, Karthikeyan Balasubramanian, Enrico Piccirillo, Abdelkader Taibah, Russo Alessandra, Jingchun He and Sanna Mario

Abstract

OBJECTIVE
The aim in this study was to review the technique and outcomes of cable graft interpositioning of the facial nerve (FN) in lateral skull base surgeries.

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The Effects of Tympanomastoid Paragangliomas on Hearing and the Audiological Outcomes after Surgery over a Long-Term Follow-Up.

The Effects of Tympanomastoid Paragangliomas on Hearing and the Audiological Outcomes after Surgery over a Long-Term Follow-Up.

2014, Audiology & Neurotology.
Sampath Chandra Prasad, Marimar Medina, Uma Patnaik, Lorenzo Lauda, Filippo Di Lella, Giuseppe De Donato, Alessandra Russoand and Mario Sanna

Abstract
The primary goals of surgery of tympanomastoid paragangliomas (TMPs) are tumor eradication and hearing preservation.

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The Role of Wait-and-Scan and the Efficacy of Radiotherapy in the Treatment of Temporal Bone Paragangliomas.

The Role of Wait-and-Scan and the Efficacy of Radiotherapy in the Treatment of Temporal Bone Paragangliomas.

2014, Otology & Neurotology, Inc.
Sampath Chandra Prasad, Hassen Ait Mimoune, Flavia D’Orazio, Marimar Medina, Andrea Bacciu, Renato Mariani-Costantini, Paolo Piazza, and Mario Sanna

Abstract
Objective: To define the role of wait-and-scan and radiotherapy (RT) in the treatment of temporal bone paragangliomas and to review the literature on the outcomes of RT as a treatment modality.

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Intraoperatively Diagnosed Cerebellopontine Angle Facial Nerve Schwannoma: How To Deal With It

Intraoperatively Diagnosed Cerebellopontine Angle Facial Nerve Schwannoma: How To Deal With It

2014, Annals of Otology, Rhinology & Laryngology
Andrea Bacciu, Marimar Medina, Mehdi Ben Ammar, Flavia D'Orazio, Filippo Di Lella, Alessandra Russo, Jacques Magnan and Mario Sanna

Abstract
Objective:This study aimed to report our experience in the management of patients with intraoperatively diagnosed intracranial facial nerve schwannomas (FNSs) and propose a decision-making strategy.

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The Behavior of Residual Tumors and Facial Nerve outcomes after incomplete Excision of Vestibular Schwannomas The Behavior of Residual Tumors and Facial Nerve outcomes after incomplete Excision of Vestibular Schwannomas

The Behavior of Residual Tumors and Facial Nerve outcomes after incomplete Excision of Vestibular Schwannomas The Behavior of Residual Tumors and Facial Nerve outcomes after incomplete Excision of Vestibular Schwannomas

2014, Journal of Neurosurgery
Zhengnong Chen, Sampath Chandra Prasad, Filippo Di Lella, Marimar Medina, Enrico Piccirillo, Abdelkader Taibah, Alessandra Russo, Shankai Yin and Mario Sanna

Abstract
Objective: The authors evaluated the behavior of residual tumors and facial nerve outcomes after incomplete excision of vestibular schwannomas (VSs).

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Indications and contraindications of auditory brainstem implants: systematic review and illustrative cases

Indications and contraindications of auditory brainstem implants: systematic review and illustrative cases

2014, European Archives of Otorhinolaryngology
Paul Merkus, Fillipo Di Lella, Giuseppe Di Trapani, Enrico Pasanisi, Milo A. Beltrame, Diego Zanetti, Maurizio Negri and Mario Sanna

Abstract
The number of non-neurofibromatosis type 2 (NF2) indications for auditory brainstem implant (ABI) in the literature is increasing. The objective of this study was to analyze and discuss the indications for ABI.

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Skull Base Chondrosarcomas: Surgical Treatment and Results

Skull Base Chondrosarcomas: Surgical Treatment and Results

2014, Annals of Otology, Rhinology & Laryngology
Ahmad Sbaihat, Andrea Bacciu, Enrico Pasanisi and Mario Sanna

Abstract
Objective: We describe our experience in the management of patients with skull base chondrosarcoma, an uncommon neoplasm of the skull base.

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Guidelines for Treating Temporal Bone Carcinoma Based on Long-Term Outcomes

Guidelines for Treating Temporal Bone Carcinoma Based on Long-Term Outcomes

2013, Otology & Neurotology, Inc.
Andrea Bacciu, Ignazio Alessandro Clemente, Enrico Piccirillo, Silvano Ferrari, and Mario Sanna

Abstract
Objective: To describe our experience in the management of patients with squamous cell carcinoma of the temporal bone (TBSCC) and to identify factors predictive of outcome.

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Salvage Surgery of Vestibular Schwannoma after failed Radiotherapy: The Gruppo Otologico experience and review of the literature

Salvage Surgery of Vestibular Schwannoma after failed Radiotherapy: The Gruppo Otologico experience and review of the literature

2013, American Journal of Otolarymgology
Sami Tanbouzi Husseini, Enrico Piccirillo, Abdelkader Taibah, Tamama Almutair, Giulio Sequino and Mario Sanna

Abstract
Objective: The use of radiation therapy has largely widespread and becomes in many centers the preference modality of treatment for symptomatic patients who are old, medically unfit for surgical therapy, those who refuse surgery and in some recurrent or residual growing tumors.

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Integrative genetic, epigenetic and pathological analysis of Paraganglioma reveals complex dysregulation of NOTCH signaling

Integrative genetic, epigenetic and pathological analysis of Paraganglioma reveals complex dysregulation of NOTCH signaling

2013, Acta Neuropathologica
Alessandro Cama, Fabio Verginelli, Lavinia Vittoria Lotti, Francesco Napolitano, Annalisa Morgano, Andria D’Orazio, Michele Vacca, Silvia Perconti, Felice Pepe, Federico Romani, Francesca Vitullo, Filippo di Lella, Rosa Visone, Massimo Mannelli, Hartmut P. H. Neumann, Giancarlo Raiconi, Carlo Paties, Antonio Moschetta, Roberto Tagliaferri, Angelo Veronese, Renato Mariani‑Costantini and Mario Sanna

Abstract
Head and neck paragangliomas, rare neoplasm of the paraganglia composed of nests of neurosecretory and glial cells embedded in vascular stroma, provide a remarkable example of organoid tumor architecture.

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Analysis of Hearing Preservation and Facial Nerve Function for Patients Undergoing Vestibular Schwannoma Surgery: The Middle Cranial Fossa Approach versus the Retrosigmoid Approach – Personal Experience and Literature Review

Analysis of Hearing Preservation and Facial Nerve Function for Patients Undergoing Vestibular Schwannoma Surgery: The Middle Cranial Fossa Approach versus the Retrosigmoid Approach – Personal Experience and Literature Review

2012, Audiology & Neurotology
Marcos Rabelo de Freitas, Alessandra Russo, Giuliano Sequino, Enrico Piccirillo and Mario Sanna

Abstract
Objective: To compare hearing preservation and facial nerve function outcomes in patients undergoing vestibular schwannoma surgery performed using either the middle cranial fossa approach (MCFA) or the retrosigmoid approach (RSA).

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